Resources

Perfusion Matters: Detecting and treating hemorrhagic shock

EMS World Supplement - The Hidden Dangers of Shock in Trauma

June 2022

Broome JM, Nordham KD, Piehl M, et al. Faster refill in an urban emergency medical services system saves lives: A prospective preliminary evaluation of a prehospital advanced resuscitative care bundle. J Trauma Acute Care Surg. 2024;96(5):702-707.

  • First study ever to demonstrate a mortality benefit for prehospital blood in urban EMS

  • The San Antonio EMS study of over 500 patients showed improvement in mortality in the ED, but could not show that more people made it out of the hospital alive

  • Odds ratio for mortality of 0.2, which means that patients who received the ARC bundle had a 20% risk of dying compared to those who didn’t receive blood

  • Scene shock index was higher for the ARC patients, but was normal at ED arrival

  • In contrast, for control patients SI was lower at the scene but had not corrected as much as in the blood group

  • Also, this study showed a dramatic reduction in prehospital intubation rate when blood was delivered early (12% vs 1.6%)

  • This mortality improvement was achieved despite a 3 minute increase in total transport time (13 minutes in controls vs 16 minutes in ARC patients)

Duchesne J, McLafferty BJ, Broome JM, et al. Every minute matters: Improving outcomes for penetrating trauma through prehospital advanced resuscitative care. J Trauma Acute Care Surg. Published online May 1, 2024.

 This is a secondary analysis of the “Faster Refill” paper above

• Evaluated the relationship between minute to first drop of blood to mortality

• Blood started at 8 minutes from EMS arrival in the ARC group, 26 minutes in the control group, who didn’t get blood started until 10 minutes after trauma center arrival

• Every minute of delay resulted in 11% increased mortality