Resources
Perfusion Matters: Detecting and treating hemorrhagic shock
EMS World Supplement - The Hidden Dangers of Shock in Trauma
June 2022
Broome JM, Nordham KD, Piehl M, et al. Faster refill in an urban emergency medical services system saves lives: A prospective preliminary evaluation of a prehospital advanced resuscitative care bundle. J Trauma Acute Care Surg. 2024;96(5):702-707.
First study ever to demonstrate a mortality benefit for prehospital blood in urban EMS
The San Antonio EMS study of over 500 patients showed improvement in mortality in the ED, but could not show that more people made it out of the hospital alive
Odds ratio for mortality of 0.2, which means that patients who received the ARC bundle had a 20% risk of dying compared to those who didn’t receive blood
Scene shock index was higher for the ARC patients, but was normal at ED arrival
In contrast, for control patients SI was lower at the scene but had not corrected as much as in the blood group
Also, this study showed a dramatic reduction in prehospital intubation rate when blood was delivered early (12% vs 1.6%)
This mortality improvement was achieved despite a 3 minute increase in total transport time (13 minutes in controls vs 16 minutes in ARC patients)
Duchesne J, McLafferty BJ, Broome JM, et al. Every minute matters: Improving outcomes for penetrating trauma through prehospital advanced resuscitative care. J Trauma Acute Care Surg. Published online May 1, 2024.
This is a secondary analysis of the “Faster Refill” paper above
• Evaluated the relationship between minute to first drop of blood to mortality
• Blood started at 8 minutes from EMS arrival in the ARC group, 26 minutes in the control group, who didn’t get blood started until 10 minutes after trauma center arrival
• Every minute of delay resulted in 11% increased mortality